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Studies: AMBLYOPIA and DiagnosticGame

 

 

1.  Hofeldt, TS, Hofeldt, AJ: BJO 1999 (see Link)

 

Topic: "Color Rivalry with Brightness Measurement"

·    24 Amblyopes 0.3 to 1.8 log defects

·    Amblyopic defect related to vision loss, p<0.0001
 

2.  Gise, R Kane SA.:  ARVO Paper #3819, 2016

Topic: "iPad Rivalrous Program in Amblyopia"

·    16 Amblyopes, all detected

·    16 Normal subjects, no false positive

·    Amblyopic defect related to vision loss, p<0.0001 (r=0.85, p<0.0001)
 

3.  Kane SA.: 2016, Unpublished to date.
Topic: "iPad Screening Program for Amblyopia"

·    211 students studied, Ages 3 to 14 years of age

·    Summary

Of the 210 children tested, there are 208 true negative, 2 true positives, zero false negative, and zero false positive.  The true positives are (1) an 8 year old undergoing treatment for amblyopia with current acuities of 20/20 OD and 20/25 OS and (2) one amblyope was detected, a 10 year old having 20/20 OD and 20/40 OS.  Of the true negatives, one child is a successfully treated amblyope having 20/20 vision in each eye; repeated inter-ocular brightness test results are 0.3 OD defect, 0.3 OS defect, and zero defect.  The sensitivity is 100% for detecting amblyopia in the 210 children. A 4-year-old child who did not understand brightness could not tested.  

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4.  Kane, SA iPad Screening of Elementary School Students with the DiagnosticGame app, 2017, active IRB study

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RESEARCH DATA

NeuroColor

COLOR VISION (289 TESTED)

     Comparison to HRR AO PLATES

·    4 Abnormal both methods (Red-Green Deficiency)

·    285 Normal both methods

RESEARCH DATA
Stereopsis

STEREOPSIS (27 TESTED)

    Comparison to Titmus

·    The P-Value is 0.000179

·    The result is significant at p < 0.05.